Areca nuts are chewed with betel leaf for their effects as a mildly stimulating, causing a hot sensation in the body, heightened alertness and sweating, although the effects vary from person to person. The areca nut contains arecoline and terpineol, which are vasocontrictoralkaloids, while the betel leaf contains eugenol, also a vasoconstrictor. The effect of chewing betel and nut is relatively mild and it could be compared to drinking a strong cup of coffee.

In East and North-East India areca nuts are not only chewed along with betel leaf but are also used in the preparation of Ayurvedic medicines. Powdered areca nut is used as a constituent in some tooth powders. Other medicinal uses include the removal of tapeworms and other intestinal parasites by swallowing a few teaspoons of powdered betel nut, or by taking tablets containing the extracted alkaloids.

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